The voice of the planet

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Belén Pedrique, Neelika Malavige, Terín Beca

Why we need a Global Dengue Alliance

Half of the world’s population is now at risk of dengue infection. There is a pressing need for an integrated approach to effectively address this growing threat to public health. While new tools for combating dengue fever have recently been developed in the field of vector control and vaccines, there is no treatment for dengue fever other than early detection and treatment of complications. The Drugs for Neglected Diseases initiative (DNDi) has recently contributed to the establishment of the Global Dengue Alliance with research institutions from dengue-endemic countries. The Alliance’s goal is to deliver a new treatment for dengue, with repurposed drugs or drug combinations, within a five-year timeframe. This initiative represents a significant leap forward by ensuring active engagement, scientific leadership, clinical guidance, and political interest from endemic countries. However, challenges persist, including the alignment of diverse partners and stakeholders, addressing knowledge gaps, leveraging information from different geographies and epidemiological settings, and securing adequate funding. Overcoming these challenges is crucial for the success of the Alliance and the development of an effective dengue treatment.

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